Cell biology: Strategy of Dis1 protein for microtubule shortening in fission yeast

Kinesin proteins eat away at microtubules, shortening them and pulling chromosomes to opposite spindle poles during cell division in most organisms. However, fission yeast lacks these proteins, and yet undergoes the same process. A recent study indicated that in fission yeast, non-kinesin proteins of the TOG/XMAP215 family promote microtubule shortening through a process known as microtubule catastrophe.

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