Mapping E. coli to overcome antibiotic resistance

Antibiotic resistance, when infection-causing bacteria evolve so they are no longer affected by typical antibiotics, is a global concern. New research has mapped the evolution and process of natural selection of Escherichia coli (E. coli) bacteria in the lab. These maps, called fitness landscapes, help us better understand the step-by-step development and characteristics of E. coli resistance to eight different drugs, including antibiotics. Researchers hope their results and methods will be useful for predicting and controlling E. coli and other bacteria in the future.

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